Invincible #18

From Robert Kirkman, Ryan Ottley, and Bill Crabtree, this 2004 Image Comics entry sends Invincible rocketing through the star-filled void alongside a massive spacecraft bearing an American flag — the cover's bold "Off to Mars!" proclamation making the destination perfectly clear. Invincible himself dominates the scene, fists clenched and cape streaming in the vacuum of space, with a distant blue planet visible behind him. It's a genuinely thrilling outer-space setup that captures exactly why the book's own cover calls itself "probably the best superhero comic book in the universe.