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The Amazing Spider-Man #210 cover
Cover: John Romita Jr. & Al Milgrom

The Amazing Spider-Man #210

Nov 1980 · Marvel · 0.50 USD
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“The Prophecy of Madame Web!”
★ 1st appearance — Madame Web★ 1st appearance — Madame Web★ 1st appearance — Cassandra Webb
About this Issue

The Amazing Spider-Man #210 is the debut issue of Madame Web (Cassandra Webb), one of the most distinctive supporting characters ever added to Spider-Man's world: a blind, paralyzed, clairvoyant mutant whose web-shaped life-support chair became one of Marvel's most visually arresting designs. By introducing a non-combatant psychic ally who immediately reveals she knows Spider-Man's secret identity, writer Denny O'Neil pushed the supporting cast in a genuinely new direction — away from physical sidekicks and toward a figure defined entirely by mystical knowledge and frailty. Over the following four decades, Cassandra Webb proved far more durable than her debut story's modest street-crime plot suggested, eventually becoming a linchpin of the 'Web of Life and Destiny' concept that underpins Spider-Verse mythology. The issue simultaneously launched John Romita Jr.'s long-running tenure as the title's penciler, a partnership that would define the visual identity of Amazing Spider-Man throughout the early-to-mid 1980s.

In "The Prophecy of Madame Web!", Spider-Man tracks a kidnapping to a mysterious clairvoyant named Debra Whitman, only to find her world is far more complex than it seems. With the help of Madame Web’s precognitive visions, Spider-Man uncovers hidden truths at the scene of the crime—and begins a new chapter in his journey as he starts her tutelage. Written by Denny O'Neil and illustrated by John Romita Jr. with inks by Joe Sinnott, this landmark issue features a striking cover by John Romita Jr. and Al Milgrom, all in a 50-cent comic from 1980.

writer Denny O'Neil · artist John Romita Jr. · artist, inker Joe Sinnott · colorist B. Sharen · letterer J. Novak · cover John Romita Jr., Al Milgrom

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Raw (Fine) $19
CGC 9.8 · 249 in census $411
CGC 9.6 · 599 in census $201
CGC 9.4 · 666 in census $134
CGC 9.2 · 466 in census $134
CGC 9.0 · 392 in census $134
CGC 8.5 · 392 in census $93
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CGC 8.0 · 306 in census $69
CGC 7.5 · 275 in census $53*
CGC 7.0 · 181 in census $47*
CGC 6.5 · 123 in census $42*
CGC 6.0 · 95 in census $42
CGC 5.5 · 65 in census $32*
CGC 5.0 · 55 in census $32*
CGC 4.5 · 39 in census $27*
CGC 4.0 · 21 in census $25*
CGC 3.5 · 15 in census $23*
CGC 3.0 · 4 in census $21*
CGC 2.5 · 2 in census $20*
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History

The issue arrived near the start of Denny O'Neil's brief but eventful return to Marvel in 1980, during which he scripted Amazing Spider-Man while also editing Daredevil through Frank Miller's landmark run. O'Neil's stated creative goal for Spider-Man was to introduce supporting players who could deepen Peter Parker's mythology without displacing him from center stage — Madame Web was the most memorable result of that ambition, designed as a blind, paraplegic psychic whose web-like life-support apparatus was conceived by her late husband Jonathan. John Romita Jr., who had joined the title two issues earlier with #208, provided breakdowns that were finished by veteran inker Joe Sinnott, with Al Milgrom and Mary Jo Duffy providing editorial oversight; critics have generally regarded O'Neil's Spider-Man run as uneven compared to his DC work, but the introduction of Madame Web stands as its clearest lasting contribution.

Trivia · 8 facts

  • First appearance of Madame Web (Cassandra Webb), a blind, paralyzed, clairvoyant mutant who operates from a spider-web-shaped life-support system designed by her late husband Jonathan Webb.
  • Story title: 'The Prophecy of Madame Web!' — written by Denny O'Neil, breakdowns by John Romita Jr., finished art by Joe Sinnott, colors by Bob Sharen, letters by Jim Novak, cover by John Romita Jr. and Al Milgrom.
  • Edited by Al Milgrom with Mary Jo Duffy as assistant editor; published with a November 1980 cover date.
  • Marks the beginning of John Romita Jr.'s approximately three-and-a-half-year regular penciling run on Amazing Spider-Man, starting with issue #208 and continuing through #250.
  • Peter Parker ends his employment at the Daily Globe in this issue.
  • J. Jonah Jameson appears in a cameo; Debbie Whitman and villain Rupert Dockery (circulation manager of the Daily Globe and kidnapping mastermind) also appear.
  • By the story's end, Madame Web discloses to Spider-Man that she already knows his secret identity — establishing the core dynamic of their relationship from her very first appearance.
  • Madame Web was later adapted into the 1994–1998 Spider-Man: The Animated Series, where she was voiced by Joan Lee (wife of Stan Lee) and became a major recurring character guiding Spider-Man through multiversal challenges; she subsequently received her own Sony live-action film in February 2024 starring Dakota Johnson. The issue is reprinted as part of the Amazing Spider-Man Epic Collection: Spider-Man — Threat or Menace? (collecting Amazing Spider-Man #207–223 and Annuals #14–15).

Cast · 5 characters

Full credits

artist, inker Joe Sinnott
colorist B. Sharen
letterer J. Novak
cover pencils John Romita Jr.
cover inks Al Milgrom

Reprints

Reprinted in Spider-Man and Hulk Weekly #416 (1981), Edderkoppen #8/1981 (1981), Spindelmannen #8/1981 (1981), Die Spinne #54 (1982), Eks almanah #327 (1982), Strange #165 (1983), El Hombre Araña / El Asombroso Hombre Araña #207 (1984), The Essential Spider-Man #9 (2009), Marvel Masterworks: The Amazing Spider-Man #20 (2018), Marvel-Verse: Spider-Man & Madame Web #[nn] (2024), Amazing Spider-Man Epic Collection #12 (2025), A Csodálatos Pókember #2, De spectaculaire Spider-Man [De spektakulaire Spiderman] #30, Homem-Aranha #21, John Romita Classic Spiderman #79, L'étonnant Spider-Man #113/114, Σπάιντερ Μαν [Spider-Man] #130, The Amazing Spider-Man #210

Key issues in The Amazing Spider-Man

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