The Amazing Spider-Man #21

Spider-Man lunges straight at the reader on this kinetic Erik Larsen and John Beatty cover, surrounded on all sides by the menacing mechanical arms and hulking robot bodies of the Spider-Slayers — barbed wire and chrome claws closing in from every angle against a city-street backdrop. The tagline "Showdown with the Spider-Slayers!" says it all: this 2000 issue from Howard Mackie and Larsen puts Peter Parker squarely in the crosshairs of some of his most relentless robotic foes. It's a visually charged chapter of the relaunched Amazing Spider-Man that fans of classic superhero action will find hard to put down.