Madame Rouge

A French actress with a split personality, Laura De Mille was recruited by the Brotherhood of Evil after the villainous Brain amplified her cruel inner nature through surgery, suppressing her gentler side and granting her a malleable, shape-shifting body.

Slithering out of the Silver Age with unmistakable menace, Madame Rouge made her debut in The Doom Patrol #86 in 1964, conjured by artist Howard Purcell for DC Comics. She's one of those gloriously sinister figures who has haunted the pages of some of DC's most beloved titles — from the strange, tragic world of the Doom Patrol alongside Robotman, Rita Farr, and Dr. Niles Caulder, to the high-stakes drama of The New Teen Titans — and her presence across more than six decades speaks to a staying power that casual readers often underestimate. With four key issues to her name and a place in Who's Who: The Definitive Directory of the DC Universe (the ultimate stamp of DC significance), Madame Rouge is exactly the kind of deep-cut Silver Age villain that rewards the collector who digs a little deeper.