The Spectacular Spider-Man #159

Part of Marvel's 1989 "Acts of Vengeance" crossover, this issue puts a freshly empowered Spider-Man front and center — literally soaring above the city skyline with the cover's bold declaration that Cosmic Spidey can now fly, "more powerful, more dangerous, more uncontrollable than ever before." Flanking him on either side are the leering, skull-like faces of the Brothers Grimm, whose magical might the cover cheekily questions even a cosmic-powered wall-crawler can handle. Sal Buscema's clean, dynamic linework sells both the exhilaration of Spider-Man's new abilities and the genuine menace of his eerily grinning opponents.