The Incredible Hulk #2 (82559-3)
In "The Missile and the Monster!", the Hulk's battle for survival reaches a shocking crescendo as Bruce Banner is caught in the High Evolutionary’s twisted experiment. Written by Stan Lee and brought to life with dynamic art by Marie Severin and inks by Herb Trimpe, this 1979 classic sees the Hulk unleashed against the New Men, culminating in a mind-bending twist where the Evolutionary evolves himself into a cosmic entity—leaving the Hulk stranded on the desolate Wundagore II. The cover, a striking collaboration by Jack Kirby and Vince Colletta, captures the epic scale of the confrontation.
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With Banner trapped and about to be evolved by the High Evolutionary, the New Men attack and stop the experiment. Banner becomes the Hulk and fights the New Men and the Evolutionary decides that the only way to stop his former creations is to do to himself what he planned on doing to Banner--evolving himself a thousand years into humanity's future. He does so and becomes a transcendent being who devolves his New Men back into animals before melting into cosmic consciousness. The Hulk is left alone on Wundagore II, the only sentient being on a lonely planet.
Plot details indexed by the Grand Comics Database (CC BY-SA).