Supergirl #72

The cover by Leonard Kirk and Robin Riggs says it all with its tagline "Two to Tangle!" — Supergirl finds herself snared in a web of energy strands, caught between a feral, blue-haired adversary and a looming feathered serpent with bared fangs overhead, while a white-clad winged figure is similarly entangled nearby. Peter David's run wraps this September 2002 issue in a lush jungle setting that feels genuinely dangerous, making the story title "Spiders and Snakes" feel perfectly apt.