Spider-Man Family #6
In "It's Not Easy Being Green," a 2008 Marvel comic written and illustrated by Chris Eliopoulos, Thor’s heroic rescue takes a bizarre turn when Loki transforms him into a frog after a grateful woman kisses him. Peter Parker, late for class and assigned to dissect a frog, quickly realizes something’s off when the creature escapes and leads him on a wild chase through Central Park. With help from a newly empowered Thor—now the Frog of Thunder—and a surprise from Mary Jane, Spider-Man teams up to confront Loki’s mischief. The cover, also by Chris Eliopoulos, captures the absurd charm of the tale.
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Thor saves a woman from being mugged and, when she kisses him as a reward, he is transformed into a frog by his evil brother, Loki. Peter arrives late for class and finds that he has to dissect a frog. When the frog breaks his glass killing jar, Peter knows something is up and Spider-Man takes the frog back to Central Park. Recovering his hammer, the frog becomes Thor, Frog of Thunder and he and Spider-Man return to face down Loki and break the curse (with a little kiss from Mary Jane to boot).
Plot details indexed by the Grand Comics Database (CC BY-SA).