Superman #226

Perched atop a skyscraper like a certain legendary giant ape, a wide-eyed, anguished Superman looms over a sprawling cityscape while military aircraft swarm around him and a figure in purple tumbles through the air nearby — it's a striking King Kong-meets-Man-of-Steel tableau that only the Silver Age could deliver. The cover blurb tells you everything you need to know: Red Kryptonite has transformed the Last Son of Krypton into a human King Kong, and he's reliving the great ape's final, desperate stand. Curt Swan's pencils and Murphy Anderson's inks bring real weight and emotion to the premise, making this May 1970 issue one of DC's more memorably offbeat Superman adventures.