Superman #21

Superman #21 kicks off "Part I of the Supergirl Saga" with a cover by John Byrne that immediately sets a striking tone — a battered Man of Steel stands amid crumbling rubble, dwarfed by the towering legs and fists of a mysterious figure in a matching red-and-blue costume looming over him. Superman's shocked expression and his own speech bubble — "It can't be! Not YOU!" — say everything about the magnitude of this encounter without giving a single thing away. Byrne and Beatty's work here promises something genuinely surprising waiting inside the pages of this September 1988 issue.