Spider-Woman #31

This October 1980 issue puts Spider-Woman in a tough spot, as the cover — penciled by Frank Miller and inked by Al Milgrom — dramatizes a startling transformation: a wheelchair-bound figure named Scotty rising and becoming the costumed, horned Hornet, who then launches a fierce aerial assault on Marvel's "most misunderstood heroine." Spider-Woman, in her red-and-yellow costume, is caught mid-battle against this winged threat, with the tagline promising she's fighting for her life against her best friend. It's a genuinely compelling setup, with the cover's sequential progression from Scotty to the Hornet giving it an energy that feels more like a page of interior storytelling than a typical splash image.