Doctor Strange, Sorcerer Supreme #45

This September 1992 Infinity War crossover puts Dr. Strange face-to-face with mortality in genuinely unsettling fashion — Geof Isherwood's cover art fills the frame with Strange's anguished face pressed against a grinning skeletal visage, its bony claw gripping his jaw in what the title perfectly describes as "Death's Cold Embrace." Roy Thomas and Isherwood bring the Sorcerer Supreme into one of Marvel's biggest early-'90s events with a cover that wastes no space and pulls no punches.