Spider-Man / Deadpool #3
In "Itsy Bitsy, Part 1," Spider-Man finds himself torn between stopping the rampaging Itsy Bitsy and the moral weight of possibly having to kill her, even as Nightcrawler tries to help him stay grounded. The mystery of Patient Zero deepens when Deadpool’s past is finally revealed—Weasel, his former friend, steps out of the shadows with a chilling hint about a darker ally. Written by Joe Kelly and brought to life with dynamic energy by Ed McGuinness, with inks by Mark Morales, colors by Jason Keith, and letters by Joe Sabino, this 2017 Marvel issue features a cover by Ed McGuinness and Mark Morales that captures the tension perfectly.
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Spider-Man spars with Nightcrawler as he grapples with facing Itsy Bitsy and whether he'll have to kill her to end her rampage. Patient Zero is finally unmasked as Deadpool's former friend Weasel, who hints darkly at his ally's identity.
Plot details indexed by the Grand Comics Database (CC BY-SA).