Namor, the Sub-Mariner #43

Marvel's self-proclaimed "first and mightiest mutant" is in serious trouble on this 1993 cover, as Namor the Sub-Mariner hurls himself fist-first toward a massive, snarling blue-skinned creature with blazing eyes and bared fangs that dwarfs him completely. M. C. Wyman's cover art captures the sheer scale of the threat beautifully, with the Sub-Mariner's trademark winged feet churning through the deep in a desperate, furious charge. "Rage at 40,000 Fathoms" promises exactly the kind of high-stakes underwater clash that makes this title such a satisfying read.