Hulk #19

Part of the "Fall of the Hulks" saga, this 2010 issue from Jeph Loeb and Ed McGuinness puts the Red Hulk on a collision course with the Fantastic Four — and the cover by McGuinness and Mark Farmer makes the stakes unmistakably clear, with a snarling Red Hulk squaring off fist-to-fist against the Thing while Mr. Fantastic, the Invisible Woman, and the Human Torch back him up amid a backdrop of fire and crumbling city blocks. It's a genuinely thrilling clash of Marvel heavyweights rendered with McGuinness's signature sense of raw, muscular energy.