Giggle Comics #22

This issue is an anthology featuring several stories. "Spencer Spook" appears on the cover with mischievous red imps. The issue includes a Lionel Trains advertisement story titled "Here's How We Got Lionel Trains," promoting the toy trains through a narrative about children convincing their father to purchase them. Another story, "The Cheese-Eaters," depicts Mulligan Mouse encountering a stranger mouse in a grocery store, and after initially quarreling over territory, they cooperate to escape a mousetrap by working together. Additional comic strips in the anthology feature humorous tales with animal characters, including one involving a character attempting various schemes with underwear and electric heated suits.