Viper

A slithering menace who first coiled into Marvel's Bronze Age in 1973, Viper made her debut in Captain America #157 under the creative hands of Steve Englehart, Steve Gerber, and Sal Buscema — a pedigree that signals serious storytelling ambition from the start. Over nearly five decades, this villain has kept remarkably dangerous company, sharing pages with the likes of Steve Rogers, Thor, and Anaconda across the storied pages of Avengers and Captain America. That kind of longevity and those kinds of co-stars speak for themselves — Viper is no footnote, but a persistent, venomous presence in Marvel's rogues' gallery worth every collector's attention.