ISAAC
ISAAC (Integral Synaptic Anti-Anionic Computer) is the vast artificial intelligence designed to manage all systems of Titan, Saturn's moon and home of the Eternal colony. Serving as the moon's governing computer, ISAAC is deeply intertwined with Titan's residents, including Mentor and Eros.
Born in the pages of Jim Starlin's landmark 1982 Marvel Graphic Novel, ISAAC is a Bronze Age creation who entered the Marvel Universe at one of its most cosmically ambitious moments. Over nearly four decades, this character has kept remarkable company — sharing adventures with the likes of Thor, Captain America, Eros, and Mentor — and has surfaced across some of Marvel's most celebrated cosmic epics, including the legendary Infinity Gauntlet saga. With appearances stretching from 1982 all the way to 2021, ISAAC may not boast the longest roster of appearances, but the caliber of the stories and characters surrounding them speaks volumes. For fans who love digging into the deeper corners of the Marvel cosmos, ISAAC is exactly the kind of discovery that makes collecting so rewarding.
#3
Top series











Covers through the years — 1983–2021
1983
1991
1994
2006
2009
2010
2014
2016
2021