Cancer

Cancer is a zodiac-themed villain who debuted as one of the Zodiac, a criminal organization whose members each take the name and identity of an astrological sign. The group clashed with the Avengers in the Silver Age of Marvel Comics.

Crawling out of the Silver Age in The Avengers #72 (1970) — courtesy of the legendary Roy Thomas and Sal Buscema — Cancer is a Marvel creation steeped in that era's bold, imaginative storytelling. With a name drawn straight from the zodiac, this character keeps striking company alongside the likes of Leo, Taurus, Sagittarius, Virgo, and Aquarius, suggesting a cosmic, sign-themed corner of the Marvel Universe that collectors have long found irresistible. Two of Cancer's appearances carry key-issue status, making even a slim seven-issue catalog punch well above its weight. For fans of deep-cut Marvel lore and the Avengers' rich Silver Age mythology, Cancer is exactly the kind of hidden gem that makes digging through back issues so rewarding.