Vault of Evil #5
In "My Friend the Ghost," a 1973 Marvel tale drawn by Tony DiPreta, a doctor and his accomplice scheme to inherit a family fortune by faking a man's death—only for the plan to take a deadly turn when the doctor betrays his friend with poison instead of a truth serum. The story unfolds with chilling precision, as the man, now truly dead, confronts the grim reality of his fate. Rich Buckler and John Romita bring the eerie atmosphere to life on the cover.
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A doctor and his friend cook up a plot to acquire the family fortune by the doctor declaring the man dead and then he pretends to return as a ghost and scare the remaining members to death. But the doctor wants all the money and betrays the man by injecting poison into him rather than a drug to make him appear dead, and so he realizes at the end of the story that he actually is a ghost. He kills the doctor.
Plot details indexed by the Grand Comics Database (CC BY-SA).