Spider-Girl #25

This double-sized anniversary issue of Spider-Girl marks a milestone for May Parker's solo series, and the cover — penciled by Patrick Olliffe and inked by Al Williamson — makes a bold statement about the odds she's facing. Spider-Girl is shown tiny and vulnerable at the center of the composition, surrounded by six menacing figures including a grinning green-and-silver villain, a snarling beast-like figure, a masked woman in white, and several other dangerous-looking adversaries collectively dubbed the Savage Six. It's a striking image that captures the sheer scale of the threat bearing down on the daughter of the true Spider-Man, and at a double-sized anniversary format, this 2000 Marvel Comics release clearly has a lot to offer fans of the series.