Marvel Universe Ultimate Spider-Man #22

Tied in with the hit Disney XD animated series, this 2014 all-ages issue teams Spider-Man with the "Guardians of the Galaxy" — and the cover sets the tone perfectly, showing a dynamic, animated-style Spidey striking a confident mid-air pose against a vast, star-filled cosmos. It's a fitting visual promise for a story that sends your friendly neighborhood wall-crawler far beyond the streets of New York. Writers Brian Michael Bendis and Joe Caramagna bring their talents to an adventure that feels as big as the universe itself.